Our principal investigators



Molecular mechanisms of Von Willebrand factor secretion
Translational research into multiple myeloma
Abnormal gene expression in acute myeloid leukemia



Prof Dr Frank Leebeek (head of department)
Pathophysiology and treatment of inherited bleeding disorders
Chromatin factors and transcriptional deregulation in blood malignancies
Fibrinogen variants and coagulation



Hematopoietic stem cell metabolism
The role of GATA2 in normal and malignant hematopoiesis
Hematopoietic stem cells and their stromal niches in health and disease



Drivers of clonal haematopoiesis and AML
Pharmacotherapy and multiple myeloma
Comprehensive analyses of acute myeloid leukemia (AML) using genomics to better understand AML biology and improve AML patient outcomes

Personalized treatment in hematology using advanced statistical methodologies